Annual report pursuant to Section 13 and 15(d)

Organization and Summary of Significant Accounting Policies - Additional Information (Detail)

v3.6.0.2
Organization and Summary of Significant Accounting Policies - Additional Information (Detail)
$ / shares in Units, $ in Thousands
12 Months Ended
Dec. 31, 2016
USD ($)
Segments
$ / shares
shares
Dec. 31, 2015
USD ($)
shares
Dec. 31, 2014
USD ($)
shares
Organization and Summary of Significant Accounting Policies [Line Items]      
Liquid investments purchased with original maturities three months or less    
Restricted cash     $ 300
Percentage of likelihood of indefinite lived intangible assets being impaired 50.00%    
Impairment charge   $ 1,870  
Change in fair value of contingent liability   $ (1,800) $ 230
Stock options and restricted stock units outstanding | shares 9,578,322 9,008,185 8,905,782
Number of operating segments | Segments 1    
Bioverativ Inc [Member] | Customer Concentration Risk [Member] | Total revenues [Member]      
Organization and Summary of Significant Accounting Policies [Line Items]      
Percentage of revenues 46.00%    
Bioverativ Inc [Member] | Change in estimated performance period [Member]      
Organization and Summary of Significant Accounting Policies [Line Items]      
Increase in net loss $ 4,300    
Increase in basic net loss per share | $ / shares $ 0.06    
Decrease in revenues $ 4,300    
Dow Agro Sciences [Member] | Customer Concentration Risk [Member] | Total revenues [Member]      
Organization and Summary of Significant Accounting Policies [Line Items]      
Percentage of revenues 26.00%    
Shire AG [Member] | Customer Concentration Risk [Member] | Total revenues [Member]      
Organization and Summary of Significant Accounting Policies [Line Items]      
Percentage of revenues 17.00% 40.00% 57.00%
Biogen Inc [Member] | Customer Concentration Risk [Member] | Total revenues [Member]      
Organization and Summary of Significant Accounting Policies [Line Items]      
Percentage of revenues   35.00% 28.00%
Minimum [Member]      
Organization and Summary of Significant Accounting Policies [Line Items]      
Estimated useful lives of related assets 3 years    
Maximum [Member]      
Organization and Summary of Significant Accounting Policies [Line Items]      
Estimated useful lives of related assets 5 years