Annual report pursuant to Section 13 and 15(d)

Accounts Payable and Accrued Liabilities - Summary of Accounts Payable and Accrued Liabilities (Detail)

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Accounts Payable and Accrued Liabilities - Summary of Accounts Payable and Accrued Liabilities (Detail) - USD ($)
$ in Thousands
Dec. 31, 2016
Dec. 31, 2015
Payables And Accruals [Abstract]    
Accounts payable $ 2,580 $ 3,905
Accrued research and development expenses 2,887 3,624
Accrued professional fees 270 356
Deferred rent 498 196
Other 26 148
Total accounts payable and accrued liabilities $ 6,261 $ 8,229