Annual report pursuant to Section 13 and 15(d)

Quarterly Financial Data (Unaudited) - Summary of Quarterly Financial Data (Detail)

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Quarterly Financial Data (Unaudited) - Summary of Quarterly Financial Data (Detail) - USD ($)
$ / shares in Units, $ in Thousands
3 Months Ended 12 Months Ended
Dec. 31, 2016
Sep. 30, 2016
Jun. 30, 2016
Mar. 31, 2016
Dec. 31, 2015
Sep. 30, 2015
Jun. 30, 2015
Mar. 31, 2015
Dec. 31, 2016
Dec. 31, 2015
Dec. 31, 2014
Selected Quarterly Financial Information [Abstract]                      
Revenues $ 8,922 $ 2,823 $ 3,702 $ 3,942 $ 9,121 $ 8,569 $ 8,358 $ 13,491 $ 19,389 $ 39,539 $ 45,870
Expenses 18,752 22,029 30,544 20,623 24,794 21,254 20,635 19,712 91,948 86,395 72,651
Net loss $ (9,624) $ (18,965) $ (26,575) $ (16,494) $ (14,013) $ (9,245) $ (12,126) $ (5,319) $ (71,658) $ (40,703) $ (26,417)
Net loss per share $ (0.14) $ (0.27) $ (0.38) $ (0.23) $ (0.20) $ (0.13) $ (0.17) $ (0.08) $ (1.02) $ (0.58) $ (0.39)