Quarterly report pursuant to Section 13 or 15(d)

Major Customers, Partnerships and Strategic Alliances - Agreement with Sigma-Aldrich Corporation - Additional Information (Detail)

v3.7.0.1
Major Customers, Partnerships and Strategic Alliances - Agreement with Sigma-Aldrich Corporation - Additional Information (Detail) - USD ($)
$ in Thousands
1 Months Ended 3 Months Ended
Oct. 31, 2009
Jul. 31, 2007
Mar. 31, 2017
Mar. 31, 2016
Research and Development Arrangement, Contract to Perform for Others [Line Items]        
Research and development     $ 12,942 $ 15,266
Sigma-Aldrich Corporation [Member]        
Research and Development Arrangement, Contract to Perform for Others [Line Items]        
Research program to develop laboratory research reagents   3 years    
Upfront license fee $ 20,000      
Public offering, common stock shares issued 636,133      
Reduced royalty rate 10.50%      
Funding available under the amended agreement $ 25,000      
Sigma-Aldrich Corporation [Member] | Upfront license fee [Member]        
Research and Development Arrangement, Contract to Perform for Others [Line Items]        
Upfront license fee 15,100      
Common stock issued under license agreement $ 4,900      
Sigma-Aldrich Corporation [Member] | License agreement terms [Member]        
Research and Development Arrangement, Contract to Perform for Others [Line Items]        
Revenues under agreement     5,000  
Research and development     $ 0 $ 0