Institutional Ownership
Shareholders
| Shareholder | Holders | Value ($MM) | % O/S | Shares |
|---|---|---|---|---|
| Institution | 296 | 1,140.58 | 66.58 | 67,975,506 |
| Mutual Fund | 244 | 463.59 | 32.45 | 33,132,241 |
| Insider | 12 | 1.76 | 0.10 | 106,040 |
Rotation
| Shareholder | Holders | Value Chg ($MM) | % O/S | Share Change |
|---|---|---|---|---|
| Buyers | 139 | 142.40 | 8.23 | 8,400,173 |
| Sellers | 146 | -168.70 | 10.01 | -10,217,629 |
| Net | -- | -26.29 | 1.78 | -1,817,456 |
Concentration
| Value ($MM) | % O/S | Shares | |
|---|---|---|---|
| Total Inst. | 1,140.58 | 66.58 | 67,975,506 |
| Top 10 Inst. | 634.12 | 37.17 | 37,948,899 |
| Top 20 Inst. | 800.41 | 46.78 | 47,759,795 |
| Top 50 Inst. | 987.90 | 57.62 | 58,821,006 |
Style
| Holders | Value ($MM) | % Inst Shares | Shares | |
|---|---|---|---|---|
| Growth | 66 | 126.45 | 7.85 | 8,017,163 |
| Aggressive Growth | 4 | 5.54 | 0.32 | 327,192 |
| Core Growth | 48 | 113.25 | 7.08 | 7,229,488 |
| Growth | 14 | 7.67 | 0.45 | 460,483 |
| Income | 6 | 8.91 | 0.52 | 529,433 |
| Income Value | 3 | 7.95 | 0.46 | 468,852 |
| Yield | 3 | 0.96 | 0.06 | 60,581 |
| Index | 30 | 443.28 | 25.63 | 26,168,520 |
| Other | 90 | 424.06 | 24.55 | 25,064,110 |
| Broker Dealer | 16 | 75.34 | 4.35 | 4,444,863 |
| GARP | 36 | 182.46 | 10.58 | 10,802,304 |
| Hedge Fund | 35 | 159.67 | 9.24 | 9,428,409 |
| Specialty | 2 | 0.72 | 0.04 | 42,429 |
| VC/Private Equi | 1 | 5.87 | 0.34 | 346,105 |
| Value | 36 | 72.61 | 4.23 | 4,317,963 |
| Core Value | 28 | 50.36 | 2.94 | 3,005,670 |
| Deep Value | 8 | 22.24 | 1.29 | 1,312,293 |
Location: Global Region
| Holders | % O/S | Shares | Share Change | |
|---|---|---|---|---|
| North America | 223 | 58.86 | 60,093,149 | 1,157,143 |
| Europe | 49 | 7.19 | 7,337,622 | 856,470 |
| Asia | 11 | 0.18 | 179,391 | 69,441 |
| Africa | 1 | 0.01 | 8,634 | -2,567 |
Top Holders
| Holder | Shares Held | % O/S | Share Change | Filing Date |
|---|---|---|---|---|
| BlackRock Institutional Trust Company, N.A. | 7,485,156 | 7.33 | 149,278 | 9/30/18 |
| The Vanguard Group, Inc. | 7,477,691 | 7.32 | -686,132 | 9/30/18 |
| State Street Global Advisors (US) | 6,512,627 | 6.38 | 431,983 | 9/30/18 |
| Wasatch Advisors, Inc. | 4,544,596 | 4.45 | 486,429 | 9/30/18 |
| Fidelity Management & Research Company | 2,656,105 | 2.60 | -662,945 | 9/30/18 |
| Credit Suisse Securities (USA) LLC | 2,184,505 | 2.14 | 415,764 | 9/30/18 |
| Credit Suisse Asset Management | 2,129,908 | 2.09 | -- | 10/31/18 |
| Casdin Capital, LLC | 2,000,000 | 1.96 | 600,000 | 9/30/18 |
| Nuveen LLC | 1,558,311 | 1.53 | 118,784 | 9/30/18 |
| Adage Capital Management, L.P. | 1,400,000 | 1.37 | -1,850,000 | 9/30/18 |
Top Holders: Mutual Funds
| Fund | Shares Held | % O/S | Share Change | Filing Date |
|---|---|---|---|---|
| SPDR S&P Biotech ETF | 4,529,367 | 4.44 | 404,451 | 9/30/18 |
| Vanguard Total Stock Market Index Fund | 2,602,172 | 2.55 | -- | 10/31/18 |
| Fidelity Select Biotechnology Portfolio | 2,395,576 | 2.35 | -260,500 | 10/31/18 |
| iShares Russell 2000 ETF | 2,290,509 | 2.24 | 60,081 | 11/30/18 |
| Credit Suisse (Lux) Glb Digital Health Equity Fd | 2,100,000 | 2.06 | -- | 10/31/18 |
| Vanguard Extended Market Index Fund | 1,368,056 | 1.34 | 1,992 | 10/31/18 |
| Vanguard Small-Cap Index Fund | 1,296,360 | 1.27 | 1,288 | 10/31/18 |
| Wasatch Small Cap Growth Fund | 1,176,257 | 1.15 | -19,556 | 9/30/18 |
| iShares NASDAQ Biotechnology ETF | 1,138,147 | 1.11 | -46,191 | 11/30/18 |
| iShares Russell 2000 Growth ETF | 923,174 | 0.90 | -49,222 | 11/30/18 |
* Insider values reflect direct beneficial ownership.
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