Institutional Ownership
Shareholders
| Shareholder | Holders | Value ($MM) | % O/S | Shares |
|---|---|---|---|---|
| Institution | 253 | 646.39 | 58.26 | 67,205,383 |
| Mutual Fund | 409 | 400.78 | 36.57 | 39,758,515 |
| Insider | 16 | 5.00 | 0.34 | 389,817 |
Rotation
| Shareholder | Holders | Value Chg ($MM) | % O/S | Share Change |
|---|---|---|---|---|
| Buyers | 113 | 94.82 | 8.54 | 9,851,233 |
| Sellers | 149 | -101.30 | 8.82 | -10,176,698 |
| Net | -6.48 | 0.28 | -325,465 |
Concentration
| Value ($MM) | % O/S | Shares | |
|---|---|---|---|
| Total Inst. | 651.66 | 58.64 | 67,646,047 |
| Top 10 Inst. | 399.58 | 36.31 | 41,884,665 |
| Top 20 Inst. | 492.81 | 44.78 | 51,657,751 |
| Top 50 Inst. | 579.48 | 52.57 | 60,641,524 |
Style
| Holders | Value ($MM) | % Inst Shares | Shares | |
|---|---|---|---|---|
| Growth | 59 | 110.31 | 9.94 | 11,463,797 |
| Aggressive Growth | 4 | 4.18 | 0.36 | 417,411 |
| Core Growth | 43 | 73.78 | 6.65 | 7,670,832 |
| Growth | 12 | 32.35 | 2.93 | 3,375,554 |
| Income | 6 | 5.93 | 0.54 | 623,384 |
| Income Value | 3 | 5.37 | 0.49 | 562,953 |
| Yield | 3 | 0.56 | 0.05 | 60,431 |
| Index | 28 | 248.26 | 22.55 | 26,011,718 |
| Other | 86 | 193.00 | 17.34 | 19,997,887 |
| Broker Dealer | 19 | 26.70 | 2.43 | 2,799,098 |
| GARP | 33 | 112.22 | 10.13 | 11,688,673 |
| Hedge Fund | 33 | 53.98 | 4.77 | 5,500,116 |
| Specialty | 1 | 0.10 | 0.01 | 10,000 |
| VC Private Equity | -- | -- | -- | -- |
| Value | 34 | 67.57 | 6.00 | 6,923,325 |
| Core Value | 28 | 62.01 | 5.50 | 6,340,932 |
| Deep Value | 6 | 5.56 | 0.50 | 582,393 |
Location: Global Region
| Holders | % O/S | Shares | Share Value | |
|---|---|---|---|---|
| North America | 200 | 49.94 | 57,605,084 | 553,971,505 |
| Europe | 52 | 8.15 | 9,400,353 | 91,110,597 |
| Asia / Pacific | 16 | 0.52 | 603,304 | 6,307,644 |
| Africa | 1 | -- | 5,360 | 90,852 |
| Middle East | -- | -- | -- | -- |
Top Holders
| Holder | Shares Held | % O/S | Share Change | Filing Date |
|---|---|---|---|---|
| The Vanguard Group, Inc. | 7,712,588 | 6.69 | 117,336 | 3/31/19 |
| BlackRock Institutional Trust Company, N.A. | 7,379,850 | 6.40 | -88,260 | 3/31/19 |
| Wasatch Advisors, Inc. | 6,437,908 | 5.58 | 1,359,170 | 3/31/19 |
| State Street Global Advisors (US) | 5,852,641 | 5.07 | -57,511 | 3/31/19 |
| Wellington Management Company, LLP | 4,313,453 | 3.74 | 2,264,728 | 3/31/19 |
| Bellevue Asset Management AG | 2,650,000 | 2.30 | 1,300,000 | 3/31/19 |
| Fidelity Management & Research Company | 2,444,750 | 2.12 | -16,400 | 3/31/19 |
| Credit Suisse Asset Management | 2,324,342 | 2.01 | -3,786 | 3/31/19 |
| Dimensional Fund Advisors, L.P. | 1,516,660 | 1.31 | 277,550 | 3/31/19 |
| Geode Capital Management, L.L.C. | 1,252,473 | 1.09 | 123,108 | 3/31/19 |
Top Holders: Mutual Funds
| Fund | Shares Held | % O/S | Share Change | Filing Date |
|---|---|---|---|---|
| SPDR S&P Biotech ETF | 3,885,394 | 3.37 | -62,427 | 3/31/19 |
| Vanguard Total Stock Market Index Fund | 3,333,128 | 2.89 | -210 | 5/31/19 |
| Fidelity Select Biotechnology Portfolio | 2,476,697 | 2.15 | 31,976 | 4/30/19 |
| Credit Suisse (Lux) Glb Digital Health Equity Fd | 2,250,000 | 1.95 | -- | 1/31/19 |
| iShares Russell 2000 ETF | 2,040,718 | 1.77 | -48,384 | 5/31/19 |
| Vanguard Extended Market Index Fund | 1,573,592 | 1.36 | -10,007 | 5/31/19 |
| Vanguard Small-Cap Index Fund | 1,488,526 | 1.29 | 14,105 | 5/31/19 |
| BB Biotech Fd | 1,350,000 | 1.17 | 1,350,000 | 12/31/18 |
| Wasatch Small Cap Growth Fund | 1,288,714 | 1.12 | 165,877 | 3/31/19 |
| Wasatch Core Growth Fund | 1,202,934 | 1.04 | 245,550 | 3/31/19 |
* Insider values reflect direct beneficial ownership.
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