Institutional Ownership
Shareholders
| Shareholder | Holders | Value ($MM) | % O/S | Shares |
|---|---|---|---|---|
| Institution | 272 | 755.32 | 57.97 | 65,617,281 |
| Mutual Fund | 251 | 365.46 | 31.91 | 36,114,511 |
| Insider | 14 | 2.58 | 0.21 | 239,373 |
Rotation
| Shareholder | Holders | Value Chg ($MM) | % O/S | Share Change |
|---|---|---|---|---|
| Buyers | 102 | 113.05 | 8.65 | 9,785,391 |
| Sellers | 147 | -113.61 | 8.77 | -9,927,770 |
| Net | -- | -0.57 | 0.12 | -142,379 |
Concentration
| Value ($MM) | % O/S | Shares | |
|---|---|---|---|
| Total Inst. | 755.32 | 57.97 | 65,617,281 |
| Top 10 Inst. | 421.11 | 32.41 | 36,682,169 |
| Top 20 Inst. | 538.34 | 41.43 | 46,894,140 |
| Top 50 Inst. | 663.63 | 51.11 | 57,853,750 |
Style
| Holders | Value ($MM) | % Inst Shares | Shares | |
|---|---|---|---|---|
| Growth | 62 | 111.45 | 8.61 | 9,745,291 |
| Aggressive Growth | 4 | 4.41 | 0.34 | 384,291 |
| Core Growth | 46 | 84.34 | 6.49 | 7,346,411 |
| Growth | 12 | 22.70 | 1.78 | 2,014,589 |
| Income | 6 | 6.11 | 0.47 | 535,112 |
| Income Value | 3 | 5.44 | 0.42 | 473,821 |
| Yield | 3 | 0.67 | 0.05 | 61,291 |
| Index | 27 | 294.92 | 22.71 | 25,703,629 |
| Other | 88 | 250.51 | 19.19 | 21,719,454 |
| Broker Dealer | 16 | 31.09 | 2.39 | 2,707,811 |
| GARP | 32 | 118.05 | 9.05 | 10,247,118 |
| Hedge Fund | 37 | 100.81 | 7.70 | 8,715,233 |
| Specialty | 3 | 0.57 | 0.04 | 49,292 |
| Value | 32 | 52.98 | 4.02 | 4,545,773 |
| Core Value | 26 | 46.34 | 3.51 | 3,967,277 |
| Deep Value | 6 | 6.64 | 0.51 | 578,496 |
Location: Global Region
| Holders | % O/S | Shares | Share Change | |
|---|---|---|---|---|
| North America | 193 | 49.25 | 55,750,420 | 562,933 |
| Europe | 46 | 7.60 | 8,602,219 | 1,727,290 |
| Asia | 15 | 0.44 | 501,465 | 312,351 |
| Africa | 2 | 0.31 | 345,360 | 336,726 |
Top Holders
| Holder | Shares Held | % O/S | Share Change | Filing Date |
|---|---|---|---|---|
| The Vanguard Group, Inc. | 7,595,252 | 6.71 | 117,561 | 12/31/18 |
| BlackRock Institutional Trust Company, N.A. | 7,468,110 | 6.60 | -17,046 | 12/31/18 |
| State Street Global Advisors (US) | 5,910,152 | 5.22 | -602,475 | 12/31/18 |
| Wasatch Advisors, Inc. | 5,078,738 | 4.49 | 534,142 | 12/31/18 |
| Fidelity Management & Research Company | 2,461,150 | 2.17 | -194,955 | 12/31/18 |
| Credit Suisse Asset Management | 2,328,128 | 2.06 | 155,200 | 12/31/18 |
| Wellington Management Company, LLP | 2,048,725 | 1.81 | 879,507 | 12/31/18 |
| Bellevue Asset Management AG | 1,350,000 | 1.19 | 1,350,000 | 12/31/18 |
| Dimensional Fund Advisors, L.P. | 1,239,110 | 1.09 | 1,017,573 | 12/31/18 |
| Northern Trust Investments, Inc. | 1,202,804 | 1.06 | -6,051 | 12/31/18 |
Top Holders: Mutual Funds
| Fund | Shares Held | % O/S | Share Change | Filing Date |
|---|---|---|---|---|
| SPDR S&P Biotech ETF | 3,885,394 | 3.43 | -62,427 | 3/31/19 |
| Vanguard Total Stock Market Index Fund | 2,892,094 | 2.56 | 197,963 | 2/28/19 |
| Fidelity Select Biotechnology Portfolio | 2,444,721 | 2.16 | -33,200 | 2/28/19 |
| Credit Suisse (Lux) Glb Digital Health Equity Fd | 2,250,000 | 1.99 | -- | 1/31/19 |
| iShares Russell 2000 ETF | 2,166,670 | 1.91 | -79,377 | 3/31/19 |
| Vanguard Extended Market Index Fund | 1,431,505 | 1.26 | 29,279 | 2/28/19 |
| BB Biotech Fd | 1,350,000 | 1.19 | 1,350,000 | 12/31/18 |
| Vanguard Small-Cap Index Fund | 1,319,949 | 1.17 | 14,553 | 2/28/19 |
| Wasatch Small Cap Growth Fund | 1,122,837 | 0.99 | -53,420 | 12/31/18 |
| iShares NASDAQ Biotechnology ETF | 1,065,045 | 0.94 | -80,394 | 3/31/19 |
* Insider values reflect direct beneficial ownership.
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