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UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, DC 20549
FORM 8-K
CURRENT REPORT PURSUANT
TO SECTION 13 OR 15(D) OF THE
SECURITIES EXCHANGE ACT OF 1934
Date of report (Date of earliest event reported): May 24, 2005
SANGAMO BIOSCIENCES, INC.
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(Exact Name of Registrant as Specified in Its Charter)
Delaware
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(State or Other Jurisdiction of Incorporation)
000-30171 68-0359556
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(Commission File Number) (IRS Employer Identification No.)
501 Canal Blvd, Suite A100 Richmond, California 94804
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(Address of Principal Executive Offices) (Zip Code)
(510) 970-6000
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(Registrant's Telephone Number, Including Area Code)
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(Former Name or Former Address, if Changed Since Last Report)
Check the appropriate box below if the Form 8-K filing is intended to
simultaneously satisfy the filing obligation of the registrant under any of the
following provisions (see General Instruction A.2. below):
[ ] Written communications pursuant to Rule 425 under the Securities
Act (17 CFR 230.425)
[ ] Soliciting material pursuant to Rule 14a-12 under the Exchange
Act (17 CFR 240.14a-12)
[ ] Pre-commencement communications pursuant to Rule 14d-2(b) under the
Exchange Act (17 CFR 240.14d-2(b))
[ ] Pre-commencement communications pursuant to Rule 13e-4(c) under the
Exchange Act (17 CFR 240.13e-4(c))
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ITEM 5.02. DEPARTURE OF DIRECTORS OR PRINCIPAL OFFICERS; ELECTION OF DIRECTORS;
APPOINTMENT OF PRINCIPAL OFFICERS.
Effective May 24, 2005, the Board of Directors of Sangamo BioSciences, Inc.
(the "Company") appointed Steven J. Mento, Ph.D. to its Board of Directors. In
addition, William Gerber, M.D. resigned from the Company's Audit Committee and
Steven Mento, Ph.D. was appointed to serve on the Company's Audit Committee
replacing Dr. Gerber.
On May 26, 2005, the Company issued a press release announcing the
appointment of Dr. Mento to the Board of Directors. A copy of the press release
is attached as Exhibit 99.1 to this Current Report on Form 8-K.
ITEM 9.01 FINANCIAL STATEMENTS AND EXHIBITS
(c) Exhibits. The following material is filed as an exhibit to this Current
Report on Form 8-K:
Exhibit No.
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99.1 Press Release Issued May 26, 2005.
SIGNATURES
Pursuant to the requirements of the Securities Exchange Act of 1934, the
Registrant has duly caused this report to be signed on its behalf by the
undersigned hereunto duly authorized.
DATE: May 26, 2005
SANGAMO BIOSCIENCES, INC.
By: /s/ EDWARD O. LANPHIER II
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Edward O. Lanphier II
President, Chief Executive Officer
Exhibit 99.1
SANGAMO BIOSCIENCES APPOINTS STEVEN MENTO, PH.D. TO ITS BOARD OF DIRECTORS
RICHMOND, Calif., May 26 /PRNewswire-FirstCall/ -- Sangamo BioSciences, Inc.
(Nasdaq: SGMO), a leader in the research and development of novel zinc finger
DNA-binding proteins (ZFPs) for therapeutic gene regulation and modification,
announced today the appointment of Steven J. Mento, Ph.D., President and CEO of
Idun Pharmaceuticals, to its Board of Directors effective May 24, 2005.
Dr. Mento has served as CEO of Idun Pharmaceuticals since 1997. Idun, which
is focused on the discovery and development of therapies to control apoptosis,
was recently acquired by Pfizer Inc. Before Idun, Dr. Mento joined Viagene, Inc.
in 1992 as Vice President of Research and Development. In 1995 Chiron
Corporation acquired the company and renamed it Chiron Viagene, Inc. Dr. Mento
served as President of Chiron Viagene, Inc. and Vice President of Chiron
Corporation until 1997. As President at Chiron Viagene, Dr. Mento had overall
responsibility for gene therapy research, product development, manufacturing and
quality control. From 1982 to 1992, Dr. Mento held various positions in research
and development at American Cyanamid Company, most recently Director, Viral
Vaccine Research and Development at Lederle-Praxis Biologicals, a business unit
of American Cyanamid.
"We are very pleased to have Dr. Mento join Sangamo's board," said Edward
Lanphier, Sangamo's president and CEO. "Steve brings extensive experience and
perspective from over 20 years in research and development and senior business
management functions in the pharmaceutical and biotechnology industry.
Additionally, he has unique experience in gene therapy research and product
development. At both Viagene and Idun, Steve was responsible for directing the
companies' transition from basic research through late-stage clinical trials. We
will no doubt gain from his knowledge as we take our ZFP Therapeutics(TM)
through the clinical trials process."
"I look forward to serving on Sangamo BioSciences' Board of Directors,"
commented Dr. Mento. "Sangamo has developed and established a robust and broadly
applicable therapeutic product development platform based upon targeting
endogenous genes with engineered ZFPs. This is an exciting period for the
company as it moves programs from the bench into clinical trials and I am eager
to aid in the company's development and progress."
Steven J. Mento, Ph.D. earned his B.A. in Microbiology, cum laude, from
Rutgers College and an M.S. and Ph.D. from Rutgers University, New Jersey. He
completed postdoctoral research at the University of Toronto, Canada and served
as a Research Assistant Professor of Medicine and Microbiology at Mount Sinai
School of Medicine from 1980-1982 before commencing his career in industry.
Dr. Mento currently serves on the Boards of Grannus BioSciences, BIO (co-
Chair of Capital Formation Committee), BIO ECS Governing Body, the University of
California San Diego (UCSD) Division of Biological Sciences Board of Advisors,
San Diego State University BioScience Center Scientific Advisory Board, Cal
State San Marcos Biotechnology Advisory Council and UCSD Bannister Family House.
From 1986 to 1992, Dr. Mento was a member of the World Health Organization (WHO)
Consultative Group on Poliomyelitis Vaccines.
About Sangamo
Sangamo BioSciences, Inc. is focused on the research and development of
novel DNA-binding proteins for therapeutic gene regulation and modification. The
most advanced ZFP Therapeutic(TM) development programs are currently in Phase I
clinical trials for evaluation of safety in patients with peripheral artery
disease and diabetic neuropathy. Other therapeutic development programs are
focused on ischemic heart disease, congestive heart failure, cancer, neuropathic
pain, and infectious and monogenic diseases. Sangamo's core competencies enable
the engineering of a class of DNA-binding proteins known as zinc finger
DNA-binding proteins (ZFPs). By engineering ZFPs that recognize a specific DNA
sequence Sangamo has created ZFP transcription factors (ZFP TF(TM)) that can
control gene expression and, consequently, cell function. Sangamo is also
developing sequence-specific ZFP Nucleases (ZFN(TM)) for therapeutic gene
modification as a treatment and possible cure for a variety of monogenic
diseases such as sickle cell anemia and for infectious diseases such as HIV. For
more information about Sangamo, visit the company's web site at www.sangamo.com
or www.expressinglife.com
This press release contains forward-looking statements regarding Sangamo's
current expectations. These statements are not guarantees of future performance
and are subject to certain risks, uncertainties and assumptions that are
difficult to predict. Factors that could cause actual results to differ include
the early stage of ZFP Therapeutic development, uncertainties related to the
timing of initiation and completion of clinical trials, and whether clinical
trial results will validate and support the safety and efficacy of ZFP
Therapeutics. Further, there can be no assurance that the necessary regulatory
approvals will be obtained or that Sangamo will be able to develop commercially
viable gene based therapeutics. Actual results may differ from those projected
in forward-looking statements due to risks and uncertainties that exist in the
company's operations and business environments. These risks and uncertainties
are described more fully in the company's' Annual Reports on Form 10-K and
Quarterly Reports on Form 10-Q as filed with the Securities and Exchange
Commission. Forward-looking statements contained in this announcement are made
as of this date and will not be updated.
SOURCE Sangamo BioSciences, Inc.
-0- 05/26/2005
/CONTACT: Elizabeth Wolffe, Ph.D. of Sangamo BioSciences, Inc.,
+1-510-970-6000, ext. 271, or ewolffe@sangamo.com; or media, Justin Jackson,
+1-212-213-0006, or investors, John Cummings, +1-415-352-6262, both of Burns
McClellan, Inc., for Sangamo BioSciences, Inc./
/Web site: http://www.sangamo.com /
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