Document And Entity Information [Abstract] Document And Entity Information [Abstract] Statement [Table] Statement [Line Items] Document Type Amendment Flag Document Period End Date Document Fiscal Year Focus Document Fiscal Period Focus Entity Registrant Name Entity Central Index Key Trading Symbol Entity Filer Category Current Fiscal Year End Date Entity Common Stock, Shares Outstanding Entity Well-known Seasoned Issuer Entity Public Float Entity Current Reporting Status Entity Voluntary Filers Consolidated Balance Sheets [Abstract] Assets [Abstract] ASSETS Cash and cash equivalents Cash and cash equivalents, end of period Cash and cash equivalents, beginning of period Cash and Cash Equivalents, at Carrying Value, Total Cash and cash equivalents Marketable securities Marketable Securities, Current, Total Marketable securities Interest receivable Interest receivable Accounts receivable Accounts Receivable, Net, Current, Total Accounts receivable Prepaid expenses Prepaid Expense, Current, Total Prepaid expenses Assets, Current Total current assets Property and equipment, net Property, Plant and Equipment, Net, Ending Balance Property, Plant and Equipment, Net, Beginning Balance Property, Plant and Equipment, Net, Total Property and equipment, net Other assets Other Assets, Total Other assets Assets Total assets Liabilities And Stockholders' Equity [Abstract] LIABILITIES AND STOCKHOLDERS' EQUITY Accounts payable and accrued liabilities Accounts Payable and Accrued Liabilities, Current, Total Accounts payable and accrued liabilities Accrued compensation and employee benefits Accrued compensation and employee benefits Deferred revenues Deferred Revenue, Current, Total Deferred revenue Liabilities, Current Total current liabilities Commitments and contingencies Commitments and contingencies Stockholders' equity: Stockholders' equity: Common stock, $0.01 par value; 80,000,000 shares authorized, 45,200,617 and 44,994,409 shares issued and outstanding at June 30, 2010 and December 31, 2009, respectively Common Stock, Value, Issued, Ending Balance Common Stock, Value, Issued, Beginning Balance Common Stock, Value, Issued, Total Common stock, $0.01 par value; 80,000,000 shares authorized, 52,554,795 and 45,377,739 shares issued and outstanding at December 31, 2011 and 2010, respectively Additional paid-in capital Additional Paid in Capital, Ending Balance Additional Paid in Capital, Beginning Balance Additional Paid in Capital, Total Additional paid-in capital Accumulated deficit Retained Earnings (Accumulated Deficit), Ending Balance Retained Earnings (Accumulated Deficit), Beginning Balance Retained Earnings (Accumulated Deficit), Total Accumulated deficit Accumulated other comprehensive income Accumulated Other Comprehensive Income (Loss), Net of Tax, Ending Balance Accumulated Other Comprehensive Income (Loss), Net of Tax, Beginning Balance Accumulated Other Comprehensive Income (Loss), Net of Tax, Total Accumulated other comprehensive income / (loss) Stockholders' Equity Attributable to Parent Balances Balances Total stockholders' equity Liabilities and Stockholders' Equity Total liabilities and stockholders' equity Common stock, par value Common stock, shares authorized Common stock, shares issued Common Stock, Shares, Issued, Total Common stock, shares outstanding Common Stock, Shares, Outstanding, Ending Balance Common Stock, Shares, Outstanding, Beginning Balance Consolidated Statements of Operations [Abstract] Revenues: Revenues: Revenue earned during the period from non-repayable sum of money awarded to an entity to carry out a specific purpose as provided in collaboration agreements. Collaboration Agreements Collaboration agreements Research grants Research grants Total revenues Total revenues Operating expenses: Operating expenses: Research and development Research and Development Expense, Total Research and development General and administrative General and Administrative Expense, Total General and administrative Total operating expenses Total operating expenses Loss from operations Loss from operations Loss from operations Interest and other income, net Nonoperating Income (Expense), Total Interest income, net Other Nonoperating Income (Expense) Other Nonoperating Income (Expense), Total Other income Net loss Net loss Net loss Net loss Net loss Earnings Per Share, Basic and Diluted Basic and diluted net loss per share Earnings Per Share, Basic and Diluted, Total The average number of shares or units issued and outstanding that are used in calculating basic and diluted EPS. Weighted Average Number of Share Outstanding Basic and Diluted Shares used in computing basic and diluted net loss per share Consolidated Statements Of Stockholders' Equity [Abstract] Statement, Equity Components [Axis] Equity Component [Domain] Equity Component [Domain] Common Stock [Member] Common Stock [Member] Additional Paid In Capital [Member] Additional Paid-In Capital [Member] Retained Earnings [Member] Accumulated Deficit [Member] Accumulated Other Comprehensive Income [Member] Accumulated Other Comprehensive Income/ (Loss) [Member] Subsidiary, Sale of Stock [Axis] Sale Of Stock Name Of Transaction [Domain] Sale of Stock, Name of Transaction [Domain] I P O [Member] Underwritten Public Offering [Member] Issuance of common stock in connection with license agreement. Issuance Of Common Stock In Connection With License Agreement [Member] License Agreements [Member] Shares, Outstanding Balances, shares Balances, shares Stock Issued During Period, Value, New Issues Issuance of common stock Stock Issued During Period, Shares, New Issues Issuance of common stock, shares Stock Issued During Period, Value, Share-based Compensation, Net of Forfeitures Issuance of common stock upon exercise of stock options and in connection with restricted stock units Stock Issued During Period, Value, Share-based Compensation, Net of Forfeitures, Total Stock Issued During Period, Shares, Share-based Compensation, Net of Forfeitures Issuance of common stock upon exercise of stock options and in connection with restricted stock units, shares Stock Issued During Period, Shares, Share-based Compensation, Net of Forfeitures, Total Stock Issued During Period, Value, Employee Stock Purchase Plan Issuance of common stock under employee stock purchase plan Stock Issued During Period, Shares, Employee Stock Purchase Plans Issuance of common stock under employee stock purchase plan, shares Adjustments to Additional Paid in Capital, Share-based Compensation, Requisite Service Period Recognition Adjustments to Additional Paid in Capital, Share-based Compensation, Requisite Service Period Recognition, Total Stock-based compensation Other Comprehensive Income (Loss), Net of Tax [Abstract] Comprehensive loss: Other Comprehensive Income (Loss), Unrealized Holding Gain (Loss) on Securities Arising During Period, Net of Tax Net unrealized gain (loss) on marketable securities Other Comprehensive Income (Loss), Net of Tax Comprehensive loss Consolidated Statements of Cash Flows [Abstract] Operating activities: Operating activities: Adjustments to reconcile net loss to net cash used in operating activities: Adjustments to reconcile net loss to net cash used in operating activities: Depreciation and amortization Depreciation and amortization Depreciation and amortization Amortization of premium / discount on marketable securities Amortization of premium / discount on marketable securities Stock-based compensatio Stock-based compensation Stock-based compensation Gain (Loss) on Sale of Property Plant Equipment Net loss on disposal of property and equipment Gain (Loss) on Sale of Property Plant Equipment, Total Net loss on disposal of property and equipment OtherNoncashIncomeExpense Other Other Noncash Income (Expense), Total Other Changes in operating assets and liabilities: Net changes in operating assets and liabilities: Increase Decrease In Accrued Interest Receivable Net Interest receivable Interest receivable Interest receivable Increase Decrease In Accounts Receivable Accounts receivable Accounts receivable Accounts receivable Prepaid expenses and other assets Prepaid expenses and other assets Prepaid expenses and other assets Prepaid expenses and other assets Increase Decrease In Other Accounts Payable And Accrued Liabilities Accounts payable and accrued liabilities Accounts payable and accrued liabilities Increase Decrease In Employee Related Liabilities Accrued compensation and employee benefits Accrued compensation and employee benefits Increase Decrease In Deferred Revenue Deferred revenue Net Cash Provided by (Used in) Operating Activities Net cash used in operating activities Investing activities: Investing activities: Payments to Acquire Marketable Securities Purchases of marketable securities Payments to Acquire Marketable Securities, Total Purchases of marketable securities Maturities of investments Maturities of marketable securities Proceeds from Sale of Investment Projects Proceeds from sales of marketable securities Purchases of property and equipment Purchases of property and equipment Payments to Acquire Property, Plant, and Equipment, Total Net Cash Provided by (Used in) Investing Activities Net cash provided by / (used in) investing activities Financing activities: Financing activities: Proceeds from issuance of common stock Issuance of common stock Net Cash Provided by (Used in) Financing Activities Net cash provided by financing activities EffectOfExchangeRateOnCashAndCashEquivalents Effect of exchange rate changes on cash Effect of exchange rate changes on cash Net decrease in cash and cash equivalents Net increase / (decrease) in cash and cash equivalents Organization And Summary Of Significant Accounting Policies [Abstract] Organization, Consolidation and Presentation of Financial Statements Disclosure and Significant Accounting Policies [Text Block] Organization And Summary Of Significant Accounting Policies Investments And Fair Value Measurement [Abstract] Investments and fair value measurement. Investments And Fair Value Measurement Text Block INVESTMENTS AND FAIR VALUE MEASUREMENT Investments And Fair Value Measurement Stock-Based Compensation [Abstract] Disclosure Of Compensation Related Costs Share Based Payments Text Block STOCK-BASED COMPENSATION Stock-Based Compensation Major Customers, Partnerships And Strategic Alliances [Abstract] dup_1_Related Party Transaction, Due from (to) Related Party, Noncurrent, Total Major customers, partnerships and strategic alliances. MAJOR CUSTOMERS, PARTNERSHIPS AND STRATEGIC ALLIANCES [Text Block] MAJOR CUSTOMERS, PARTNERSHIPS AND STRATEGIC ALLIANCES Major Customers, Partnerships And Strategic Alliances Property And Equipment [Abstract] Property, Plant and Equipment Disclosure [Text Block] Property And Equipment Commitments. Commitments [Abstract] Commitments Disclosure [Text Block] Commitments Stockholders' Equity [Abstract] Stockholders' Equity Note Disclosure [Text Block] Stockholders' Equity Comprehensive Loss [Abstract] COMPREHENSIVE LOSS. Comprehensive Loss Income Taxes [Abstract] Income Tax Disclosure [Text Block] Income Taxes Accounts Payable And Accrued Liabilities [Abstract] Accounts Payable and Accrued Liabilities Disclosure [Text Block] Accounts Payable And Accrued Liabilities Quarterly Financial Data [Abstract] Quarterly Financial Information [Text Block] Quarterly Financial Data Subsequent Event [Abstract] Subsequent Events [Text Block] Subsequent Event