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    <dei:AmendmentDescription contextRef="c-1" id="f-34">Sangamo Therapeutics, Inc. (the &#x201c;Company,&#x201d; &#x201c;Sangamo,&#x201d; &#x201c;we,&#x201d; &#x201c;us,&#x201d; or &#x201c;our&#x201d;) is filing this Amendment&#160;No.&#160;1 on Form&#160;10-K/A (this &#x201c;Amendment&#160;No.&#160;1&#x201d;) to amend our Annual Report on Form&#160;10-K for the year ended December 31, 2025, originally filed with the Securities and Exchange Commission (the &#x201c;SEC&#x201d;) on March 30, 2026 (the &#x201c;Original Form&#160;10-K,&#x201d; together with Amendment&#160;No.&#160;1, our &#x201c;Annual Report&#x201d;), solely for the purpose of including the information required by Part&#160;III of Form&#160;10-K. This information was previously omitted from the Original Form 10-K in reliance on General Instruction G(3) to Form&#160;10-K, which permits the information in the above-referenced items to be incorporated in the Form 10-K by reference to our definitive proxy statement if such statement is filed no later than 120 days after our fiscal year-end. We are filing this Amendment&#160;No.&#160;1 to include information required in Items&#160;10 through 14 of Part III of Form&#160;10-K because our definitive proxy statement containing such information will not be filed with the SEC within 120 days after the end of the fiscal year covered by the Original Form&#160;10-K. The reference on the cover of the Original Form&#160;10-K to the incorporation by reference to portions of our definitive proxy statement into Part III of the Original Form&#160;10-K is hereby deleted.In accordance with Rules 12b-15 and 13a-14 under the Securities Exchange Act of 1934, as amended (the &#x201c;Exchange&#160;Act&#x201d;), we have also amended Part IV, Item 15 to include currently dated certifications pursuant to Section 302 of the Sarbanes-Oxley Act of 2002 from our principal executive officer and principal financial officer. Because no financial statements have been included in this Amendment&#160;No.&#160;1 and this Amendment&#160;No.&#160;1 does not contain or amend any disclosure with respect to Items&#160;307 and 308 of Regulation&#160;S-K, paragraphs&#160;3,&#160;4&#160;and&#160;5 of the certifications have been omitted. Similarly, because no financial statements have been included in this Amendment&#160;No.&#160;1, certifications pursuant to Section&#160;906 of the Sarbanes-Oxley Act of 2002 have been omitted.Except as described above, this Amendment&#160;No.&#160;1 does not modify or update disclosure in, or exhibits to, the Original Form&#160;10-K. Furthermore, this Amendment&#160;No.&#160;1 does not change any previously reported financial results, nor does it reflect events occurring after the date of the Original Form&#160;10-K. Information not affected by this Amendment&#160;No.&#160;1 remains unchanged and reflects the disclosures made at the time the Original Form&#160;10-K was filed. Accordingly, this Amendment&#160;No.&#160;1 should be read in conjunction with the Original Form&#160;10-K and our other filings with the SEC.</dei:AmendmentDescription>
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    <ecd:AwardTmgMnpiDiscTextBlock contextRef="c-1" id="f-42">From time to time, the Company grants equity awards, including stock options, to its employees and members of the Board. Equity awards are generally granted to employees, including executives, when they are hired, and employees are eligible for additional equity awards in connection with annual performance reviews each year or as otherwise determined appropriate by our Compensation Committee or Board.&lt;div style="margin-top:6pt;text-indent:36pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',serif;font-size:10pt;font-weight:400;line-height:120%"&gt;We maintain written procedures for the timing of granting stock options and RSUs to our employees. Our equity grant procedures in place during 2025 provide that options and/or RSUs granted to new employees or for mid-year promotions are generally granted on the 10th&#160;day of the month (the &#x201c;monthly grant date&#x201d;) immediately following the month of the employee&#x2019;s hire date or promotion date (or if such day was not a trading day, the immediately preceding trading day). However, if we believe we may be in possession of material, nonpublic information (&#x201c;MNPI&#x201d;) on a monthly grant date, we will generally delay the grant of the award to the next monthly grant date. For annual equity awards (which may consist of options and/or RSUs) granted to employees, our equity grant procedures provide that such awards are granted on the 25th&#160;day of February, or the last trading day preceding the 25th&#160;of February, unless otherwise determined by the Board or Compensation Committee.&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-top:6pt;text-indent:36pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',serif;font-size:10pt;font-weight:400;line-height:120%"&gt;Our non-employee directors receive grants of initial and annual awards at the time of a director&#x2019;s initial appointment or election to the Board and at the time of each annual meeting of the Company&#x2019;s stockholders, which are granted automatically pursuant to the terms of our Automatic Director Grant Program under our 2018&#160;Plan, as further described under the heading, &#x201c;Director Compensation&#x2014;Equity Incentives Granted under our 2018&#160;Plan&#x201d; below. &lt;/span&gt;&lt;/div&gt;&lt;div style="margin-top:6pt;text-indent:36pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',serif;font-size:10pt;font-weight:400;line-height:120%"&gt;The Company does not grant equity awards in anticipation of the release of MNPI and we do not time the release of MNPI based on equity award grant dates or for the purposes of affecting the value of executive compensation.&lt;/span&gt;&lt;/div&gt;</ecd:AwardTmgMnpiDiscTextBlock>
    <ecd:AwardTmgMethodTextBlock contextRef="c-1" id="f-41">From time to time, the Company grants equity awards, including stock options, to its employees and members of the Board. Equity awards are generally granted to employees, including executives, when they are hired, and employees are eligible for additional equity awards in connection with annual performance reviews each year or as otherwise determined appropriate by our Compensation Committee or Board.&lt;div style="margin-top:6pt;text-indent:36pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',serif;font-size:10pt;font-weight:400;line-height:120%"&gt;We maintain written procedures for the timing of granting stock options and RSUs to our employees. Our equity grant procedures in place during 2025 provide that options and/or RSUs granted to new employees or for mid-year promotions are generally granted on the 10th&#160;day of the month (the &#x201c;monthly grant date&#x201d;) immediately following the month of the employee&#x2019;s hire date or promotion date (or if such day was not a trading day, the immediately preceding trading day). However, if we believe we may be in possession of material, nonpublic information (&#x201c;MNPI&#x201d;) on a monthly grant date, we will generally delay the grant of the award to the next monthly grant date. For annual equity awards (which may consist of options and/or RSUs) granted to employees, our equity grant procedures provide that such awards are granted on the 25th&#160;day of February, or the last trading day preceding the 25th&#160;of February, unless otherwise determined by the Board or Compensation Committee.&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-top:6pt;text-indent:36pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',serif;font-size:10pt;font-weight:400;line-height:120%"&gt;Our non-employee directors receive grants of initial and annual awards at the time of a director&#x2019;s initial appointment or election to the Board and at the time of each annual meeting of the Company&#x2019;s stockholders, which are granted automatically pursuant to the terms of our Automatic Director Grant Program under our 2018&#160;Plan, as further described under the heading, &#x201c;Director Compensation&#x2014;Equity Incentives Granted under our 2018&#160;Plan&#x201d; below. &lt;/span&gt;&lt;/div&gt;&lt;div style="margin-top:6pt;text-indent:36pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',serif;font-size:10pt;font-weight:400;line-height:120%"&gt;The Company does not grant equity awards in anticipation of the release of MNPI and we do not time the release of MNPI based on equity award grant dates or for the purposes of affecting the value of executive compensation.&lt;/span&gt;&lt;/div&gt;</ecd:AwardTmgMethodTextBlock>
    <ecd:AwardTmgHowMnpiCnsdrdTextBlock contextRef="c-1" id="f-40">From time to time, the Company grants equity awards, including stock options, to its employees and members of the Board. Equity awards are generally granted to employees, including executives, when they are hired, and employees are eligible for additional equity awards in connection with annual performance reviews each year or as otherwise determined appropriate by our Compensation Committee or Board.&lt;div style="margin-top:6pt;text-indent:36pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',serif;font-size:10pt;font-weight:400;line-height:120%"&gt;We maintain written procedures for the timing of granting stock options and RSUs to our employees. Our equity grant procedures in place during 2025 provide that options and/or RSUs granted to new employees or for mid-year promotions are generally granted on the 10th&#160;day of the month (the &#x201c;monthly grant date&#x201d;) immediately following the month of the employee&#x2019;s hire date or promotion date (or if such day was not a trading day, the immediately preceding trading day). However, if we believe we may be in possession of material, nonpublic information (&#x201c;MNPI&#x201d;) on a monthly grant date, we will generally delay the grant of the award to the next monthly grant date. For annual equity awards (which may consist of options and/or RSUs) granted to employees, our equity grant procedures provide that such awards are granted on the 25th&#160;day of February, or the last trading day preceding the 25th&#160;of February, unless otherwise determined by the Board or Compensation Committee.&lt;/span&gt;&lt;/div&gt;&lt;div style="margin-top:6pt;text-indent:36pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',serif;font-size:10pt;font-weight:400;line-height:120%"&gt;Our non-employee directors receive grants of initial and annual awards at the time of a director&#x2019;s initial appointment or election to the Board and at the time of each annual meeting of the Company&#x2019;s stockholders, which are granted automatically pursuant to the terms of our Automatic Director Grant Program under our 2018&#160;Plan, as further described under the heading, &#x201c;Director Compensation&#x2014;Equity Incentives Granted under our 2018&#160;Plan&#x201d; below. &lt;/span&gt;&lt;/div&gt;&lt;div style="margin-top:6pt;text-indent:36pt"&gt;&lt;span style="color:#000000;font-family:'Times New Roman',serif;font-size:10pt;font-weight:400;line-height:120%"&gt;The Company does not grant equity awards in anticipation of the release of MNPI and we do not time the release of MNPI based on equity award grant dates or for the purposes of affecting the value of executive compensation.&lt;/span&gt;&lt;/div&gt;</ecd:AwardTmgHowMnpiCnsdrdTextBlock>
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